LOGGIC Core BioClinical Data Bank

Gender: All
Maximum age: 20 Years
Minimum age: None
Inclusion criteria: - Age < 21 years.

- Histologically verified LGG
Exceptions (i.e. MRI based diagnosis) can be accepted only where a biopsy would pose an unacceptable risk to damage of eloquent brain structures.

- Primary diagnosis or at relapse/progression

- At primary diagnosis:
- Histologically verified low-grade glioma / glioneuronal tumour WHO
grade I or II.
- Fresh frozen and paraffin tumour material together with blood available
for molecular diagnostics.

-At relapse/progression:
-Fresh frozen and paraffin tumour material together with blood available
for molecular diagnostics from primary diagnosis and/or current episode
(preferably) of relapse/progression.
- No exceptions for the submission of fresh frozen and paraffin tumour
material with blood

- In case that the date of diagnosis is earlier than the start of LOGGIC Core in a country, submission of fresh frozen and paraffin tumour material together with blood is mandatory with no exceptions (in other words, one can include ?retrospective cases? only if material is available).

- Before patient registration, written informed consent, including data and tumour material transfer, must be given according to ICH/GCP, and national/local regulations.

- Residency in one of the participating countries of LOGGIC Core.
Exclusion criteria: No LGG