Nikotinhaltige E-Zigaretten (Vaporizer) zur Unterstützung der Rauchentwöhnung: Nutzen, Sicherheit und Toxikologie

Other: ENDS (vaporizer/e-cig) and smoking cessation counseling;Other: Smoking cessation counseling

Inclusion Criteria:

- Informed Consent as documented by signature

- Persons aged 18 or older

- Currently smoking 5 or more cigarettes a day for at least 12 months

- Willing to try to quit smoking within the next 3 months,

- Persons providing a valid phone number, a valid email address and/or a valid postal
address.

Exclusion Criteria:

- Known hypersensitivity or allergy to contents of the e-liquid

- Participation in another study with investigational drug within the 30 days preceding
the baseline visit and during the present study where interactions are to be expected

- Women who are pregnant or breast feeding

- Intention to become pregnant during the course of the scheduled study intervention,
i.e. within the first 6-months of the study

- Persons having used ENDS regularly in the 3 months preceding the baseline visit

- Persons having used nicotine replacement therapy (NRT) or other medications with
demonstrated efficacy as an aid for smoking cessation such as varenicline or bupropion
within the 3 months preceding the baseline visit

- Persons who cannot attend the 6- month follow-up visit for any reason

- Cannot understand instructions delivered in person or by phone, or otherwise unable to
participate in study procedures